γ-谷氨酰转肽酶 来源于马肾脏
γ-谷氨酰转肽酶 来源于马肾脏结构式
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常用名 | γ-谷氨酰转肽酶 来源于马肾脏 | 英文名 | Gamma glutamyltransferase |
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| CAS号 | 9046-27-9 | 分子量 | 363.496 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 555.1±50.0 °C at 760 mmHg | |
| 分子式 | C23H29N3O | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 290.5±28.8 °C |
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Inhibition of human γ-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.
Biochem. J. 450(3) , 547-57, (2013) GGT (γ-glutamyl transpeptidase) is an essential enzyme for maintaining cysteine homoeostasis, leukotriene synthesis, metabolism of glutathione conjugates and catabolism of extracellular glutathione. Overexpression of GGT has been implicated in many pathologie... |
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Cardiohepatic interactions in heart failure: an overview and clinical implications.
J. Am. Coll. Cardiol. 61(24) , 2397-405, (2013) Heart failure (HF) is a major public health problem leading to frequent hospitalizations, impaired quality of life, and shortened life expectancy. Heart failure leads to a chronic inability to meet metabolic requirements of end organs or skeletal muscle. Curr... |
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Pancreatic complications in pediatric choledochal cysts.
J. Pediatr. Surg. 48(9) , 1897-902, (2013) The aim of this study is to clarify the clinical features and risk factors of pre- and postoperative pancreatic complications in pediatric choledochal cysts.A retrospective chart review was carried out on pediatric patients with choledochal cysts who underwen... |
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Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion.
Biochim. Biophys. Acta 1844(9) , 1523-9, (2014) γ-Glutamyltranspeptidases (γ-GTs) cleave the γ-glutamyl amide bond of glutathione and transfer the released γ-glutamyl group to water (hydrolysis) or acceptor amino acids (transpeptidation). These ubiquitous enzymes play a key role in the biosynthesis and deg... |
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The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress.
J. Nutr. 144(3) , 273-81, (2014) Undernutrition contributes to half of all childhood deaths under the age of 5 y, and confers upon survivors a life-long predisposition to obesity, type 2 diabetes, and cardiovascular disease. Mechanisms underlying the link between early nutrient deprivation a... |
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A new class of NO-donor pro-drugs triggered by γ-glutamyl transpeptidase with potential for reno-selective vasodilatation.
Chem. Commun. (Camb.) 49(14) , 1389-91, (2013) This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of γ-glutamyl transpeptidase (γ-GT), and have potential for the treatment of acute renal injury/failure (A... |
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Fenugreek seeds, a hepatoprotector forage crop against chronic AlCl3 toxicity.
BMC Vet. Res. 9 , 22, (2013) Having considered how bioavailable aluminium (Al) may affect ecological systems and animals living there, especially cattle, and in search for a preventive dietary treatment against Al toxicity, we aimed to test the protective role of fenugreek seeds against ... |
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γ-glutamyl transpeptidase 1 specifically suppresses green-light avoidance via GABAA receptors in Drosophila.
J. Neurochem. 130(3) , 408-18, (2014) Drosophila larvae innately show light avoidance behavior. Compared with robust blue-light avoidance, larvae exhibit relatively weaker green-light responses. In our previous screening for genes involved in larval light avoidance, compared with control w(1118) ... |
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Metabolic and histopathological profile of Rattus norvegicus (Wistar) experimentally infected by Angiostrongylus cantonensis (Chen, 1935).
Exp. Parasitol. 137 , 35-40, (2014) Eosinophilic meningitis is a disease characterized by increased eosinophils in the cerebrospinal fluid (CSF), which is the most commonly caused by invasion of the central nervous system by helminths, as occurs in Angiostrongylus cantonensis infections. The ro... |
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The one year exercise and lifestyle intervention program KLAKS: Effects on anthropometric parameters, cardiometabolic risk factors and glycemic control in childhood obesity.
Metab. Clin. Exp. 63(3) , 422-30, (2014) Regular physical exercise within structured lifestyle programs may improve weight status and minimize metabolic risk factors in childhood obesity. The aim of this study was to evaluate the effect of the one-year combined physical exercise/lifestyle program KL... |