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角蝰毒素 S6c

角蝰毒素 S6c结构式
角蝰毒素 S6c结构式
品牌特惠专场
常用名 角蝰毒素 S6c 英文名 Sarafotoxin C trifluoroacetate salt
CAS号 121695-87-2 分子量 2515.75000
密度 N/A 沸点 N/A
分子式 C103H147N27O37S5 熔点 N/A
MSDS 中文版 美版 闪点 N/A

Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.

Biochem. Biophys. Res. Commun. 175 , 556-561, (1991)

In contrast to endothelin-1 (ET-1) and several of its analogues, sarafotoxin S6c (S6c) was a much more potent inhibitor of [125I]-ET-1 binding in rat hippocampus and cerebellum (Ki approximately 20 pM) than in rat atria and aorta (Ki approximately 4500 nM), s...

Mechanisms of endothelin-induced venoconstriction in isolated guinea pig mesentery.

J. Pharmacol. Exp. Ther. 289 , 762-767, (1999)

In the present study, endothelin (ET) agonists and receptor selective antagonists were used to characterize ET receptors mediating constriction in guinea pig mesenteric veins (250-300 micrometers diameter) in vitro. The contribution of ET-evoked vasodilator r...

Influence of endothelins and sarafotoxin 6c and L-NAME on renal vasoconstriction in the anaesthetized rat.

Br. J. Pharmacol. 128 , 809-815, (1999)

1. An investigation was performed in pentobarbitone anaesthetized rats to compare the renal vasoconstrictor actions of endothelin-1 (ET-1), endothelin-3 (ET-3) and sarafotoxin 6c and their dependency on NO production. 2. Intra-renal arterial infusion of ET-1 ...