N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯
N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯结构式
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常用名 | N-(叔丁氧羰基)-L-谷氨酸-1-苄基酯 | 英文名 | Boc-L-glutamic acid 1-benzyl ester |
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| CAS号 | 30924-93-7 | 分子量 | 337.368 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 522.6±50.0 °C at 760 mmHg | |
| 分子式 | C17H23NO6 | 熔点 | 97 °C | |
| MSDS | 中文版 美版 | 闪点 | 269.9±30.1 °C |
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Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter.
Eur. J. Pharm. Sci. 11 , 43-50, (2000) One approach to increase drug stability and to facilitate oral absorption of low bioavailability drugs may be to design oligopeptide ester prodrugs which are stable in the gastrointestinal tract, are transported via the oligopeptide transporter, and finally r... |
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Side reactions in solid-phase peptide synthesis and their applications.
Int. J. Pept. Protein Res. 48 , 292-298, (1996) Side reactions in peptide synthesis indicate steps needing improvement as well as opportunities for structural diversification in combinatorial design. Among the side reactions observed in this study, transesterification of Boc-Glu(OBzl) occurred in TMAH-cata... |
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Modification of the vitamin K-dependent carboxylase assay.
J. Biochem. Biophys. Methods 11 , 59, (1985) Methods are presented that describe alternative protocols for the isolation of rat liver microsomes containing the vitamin K-dependent carboxylase and the procedure in which the solubilized enzyme is assayed. The method for determining the rate of 14CO2 incor... |
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Structure-activity studies on prolactin-releasing peptide (PrRP). Analogues of PrRP-(19-31)-peptide.
J. Pept. Sci. 11 , 161-165, (2005) An investigation of a series of single replacement analogues of PrRP-(19-31)-peptide has shown that good functional activity was retained when Phe31 was replaced with His(Bzl), Phe(4Cl), Nle, Trp, Cys(Bzl) or Glu(OBzl); when Val28 or Ile25 was replaced with P... |