3-甲氧基-4-羟基扁桃酸
3-甲氧基-4-羟基扁桃酸结构式
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常用名 | 3-甲氧基-4-羟基扁桃酸 | 英文名 | Vanillyl mandelic acid |
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| CAS号 | 55-10-7 | 分子量 | 198.173 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 421.3±45.0 °C at 760 mmHg | |
| 分子式 | C9H10O5 | 熔点 | 132-134 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 173.7±22.2 °C |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Lipophilicity of amine neurotransmitter precursors, metabolites and related drugs estimated on various TLC plates.
J. Chromatogr. Sci. 52(9) , 1095-103, (2014) The retention behavior for a series of amine neurotransmitters, their precursors, metabolites and structurally related drugs has been investigated in reversed-phase thin-layer chromatography using RP-18, RP-8, RP-2, CN and Diol stationary phases and mixtures ... |
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A reliable and simple method for the assay of neuroendocrine tumor markers in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry.
Anal. Chim. Acta 759 , 66-73, (2013) Homovanillic acid (HVA), vanylmandelic acid (VMA), and 5-hydroxyindoleacetic acid (5-HIAA) are the metabolites of some catecholamines such as epinephrine, nor-epinephrine, dopamine and serotonin and their quantification is used in the diagnosis and management... |
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Selective extraction and analysis of catecholamines in rat blood microdialysate by polymeric ionic liquid-diphenylboric acid-packed capillary column and fast separation in high-performance liquid chromatography-electrochemical detector.
J. Chromatogr. A. 1409 , 125-31, (2015) Concentration of blood catecholamines (CAs) is linked to a host of cardiovascular diseases, including hypertension and stenocardia. The matrix interferences and low concentration require tedious sample pretreatment methods before quantitative analysis by the ... |
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Preanalytical validation and reference values for a mass spectrometric assay of serum vanillylmandelic acid for screening of catecholamine secreting neuroendocrine tumors.
Clin. Chim. Acta 446 , 206-12, (2015) Urinary vanillylmandelic acid (VMA) is used to diagnose and monitor catecholamine secreting neuroendocrine tumors (NETs). We developed and validated a new liquid chromatography tandem mass spectrometry (LC-MS/MS) assay for determination of serum VMA.We used s... |
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Sensitive, rapid and easy analysis of three catecholamine metabolites in human urine and serum by liquid chromatography tandem mass spectrometry.
J. Chromatogr. Sci. 50 , 450-6, (2012) A sensitive and easy analytical method for catecholamine metabolites including 4-hydroxy-3-methoxyphenylglycol sulfate (HMPG sulfate), vanillylmandelic acid (VMA) and homovanillic acid (HVA) determination was developed based on liquid chromatography-tandem ma... |
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Characterization of neuroblastic tumors using 18F-FDOPA PET.
J. Nucl. Med. 54(1) , 42-9, (2013) Neuroblastic tumors are childhood neoplasms that possess amino acid decarboxylase (AADC) activity and can theoretically be imaged by (18)F-fluorodihydroxyphenylalanine ((18)F-FDOPA) PET, a new diagnostic tool for neuroendocrine tumors. In this study, we explo... |
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MIBG molecular imaging for evaluating response to chemotherapy in patients with malignant pheochromocytoma: preliminary results.
Cancer Imaging 13 , 155-61, (2013) Malignant pheochromocytomas respond to chemotherapy with a reduction in tumor size and catecholamine secretion. We investigated the usefulness of molecular imaging with meta-iodobenzylguanidine (MIBG) for evaluating the effects of chemotherapy in patients wit... |
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Left-sided giant adrenal myelolipoma secreting catecholamine.
Indian J. Pathol. Microbiol. 55(3) , 389-91, (2012) Adrenal myelolipoma (AML) is a rare benign tumor composed of mature adipose and hematopoietic tissue. Most of these patients are asymptomatic and the tumors are non-secreting. We present a case with a large functional adrenal myelolipoma, wherein the patient ... |
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Diagnosis and treatment of 29 cases of adrenal ganglioneuroma.
Eur. Rev. Med. Pharmacol. Sci. 17(8) , 1110-3, (2013) To evaluate diagnosis and treatment experience for adrenal ganglioneuroma and provide data for clinical surgery. |