氯酚红-Beta-D-半乳吡喃糖苷
氯酚红-Beta-D-半乳吡喃糖苷结构式
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常用名 | 氯酚红-Beta-D-半乳吡喃糖苷 | 英文名 | chlorophenol red-beta-d-galactopyranosid |
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| CAS号 | 99792-79-7 | 分子量 | 585.407 | |
| 密度 | 1.661 | 沸点 | N/A | |
| 分子式 | C25H22Cl2O10S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Trypanocidal Activity of Long Chain Diamines and Aminoalcohols.
Molecules 20 , 11554-68, (2015) Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0-6.6 times) than the reference compound nifurtimox. From them, three aminoal... |
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Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.
Oncotarget 6 , 16488-506, (2015) Malignant melanoma is the most dangerous type of skin cancer. Although recent progress in treatment has been achieved, lack of response, drug resistance and relapse remain major problems. The tumor suppressor p53 is rarely mutated in melanoma, yet it is inact... |
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2-Aminothiazolones as anti-HIV agents that act as gp120-CD4 inhibitors.
Antimicrob. Agents Chemother. 58(6) , 3043-52, (2014) We report here the synthesis of 2-aminothiazolones along with their biological properties as novel anti-HIV agents. Such compounds have proven to act through the inhibition of the gp120-CD4 protein-protein interaction that occurs at the very early stage of th... |
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Multiple roles for Enterococcus faecalis glycosyltransferases in biofilm-associated antibiotic resistance, cell envelope integrity, and conjugative transfer.
Antimicrob. Agents Chemother. 59 , 4094-105, (2015) The emergence of multidrug-resistant bacteria and the limited availability of new antibiotics are of increasing clinical concern. A compounding factor is the ability of microorganisms to form biofilms (communities of cells encased in a protective extracellula... |
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Immune response profile elicited by the model antigen ovalbumin expressed in fusion with the bacterial OprI lipoprotein.
Mol. Immunol. 64(1) , 36-45, (2015) The use of immunogenic formulations targeting pattern recognition receptors towards modulation of immune responses is a promising strategy to develop better vaccines against infectious and malignant diseases. Molecules targeting TLR2 offer interesting propert... |
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Aerobic glycolysis tunes YAP/TAZ transcriptional activity.
EMBO J. 34 , 1349-70, (2015) Increased glucose metabolism and reprogramming toward aerobic glycolysis are a hallmark of cancer cells, meeting their metabolic needs for sustained cell proliferation. Metabolic reprogramming is usually considered as a downstream consequence of tumor develop... |
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Enhancement of MHC-I antigen presentation via architectural control of pH-responsive, endosomolytic polymer nanoparticles.
AAPS J. 17(2) , 358-69, (2015) Protein-based vaccines offer a number of important advantages over organism-based vaccines but generally elicit poor CD8(+) T cell responses. We have previously demonstrated that pH-responsive, endosomolytic polymers can enhance protein antigen delivery to ma... |
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Detection of marine microalgal biotoxins using bioassays based on functional expression of tunicate xenobiotic receptors in yeast.
Toxicon 95 , 13-22, (2015) Marine microalgae can produce biotoxins that cause widespread poisoning in marine ecosystems and may also affect human health. While established microalgal biotoxins are detectable using chemical methods, a need remains for robust, inexpensive bioassays. Liga... |
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Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8(+) T cell responses.
J. Control. Release 191 , 24-33, (2014) Synthetic subunit vaccines need to induce CD8(+) cytotoxic T cell (CTL) responses for effective vaccination against intracellular pathogens. Most subunit vaccines primarily generate humoral immune responses, with a weaker than desired CD8(+) cytotoxic T cell ... |
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A robust lentiviral pseudotype neutralisation assay for in-field serosurveillance of rabies and lyssaviruses in Africa.
Vaccine 27(51) , 7178-86, (2009) The inflexibility of existing serological techniques for detection of rabies in surveillance constrains the benefit to be gained from many current control strategies. We analysed 304 serum samples from Tanzanian dogs for the detection of rabies antibodies in ... |