芸苔素内酯
芸苔素内酯结构式
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常用名 | 芸苔素内酯 | 英文名 | Isohomobrassinolide |
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| CAS号 | 80483-89-2 | 分子量 | 494.704 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 643.0±55.0 °C at 760 mmHg | |
| 分子式 | C29H50O6 | 熔点 | 193-194ºC | |
| MSDS | 中文版 美版 | 闪点 | 203.2±25.0 °C |
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Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells.
J. Med. Chem. 54 , 4057-4066, (2011) Brassinosteroids are plant-derived polyhydroxylated derivatives of 5α-cholestane, structurally similar to cholesterol-derived animal steroid hormones and insect ecdysteroids. In this study, we synthesized a set of brassinosteroid analogues of a natural brassi... |
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Brassinosteroids protect Lycopersicon esculentum from cadmium toxicity applied as shotgun approach.
Protoplasma 239(1-4) , 3-14, (2010) Surface-sterilized seeds of two tomato cultivars (cv. K-25 and Sarvodya) were soaked in 100 microM CdCl(2) for 8 h (shotgun approach). The resulting 59-day-old seedlings were sprayed with 10(-8) M of 28-homobrassinolide (HBL) or 24-epibrassinolide (EBL) to th... |
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Synthesis and bioactivity of natural and C-3 fluorinated biosynthetic precursors of 28-homobrassinolide.
Phytochemistry 58(6) , 973-80, (2001) In this paper we describe the synthesis of two new fluorinated brassinosteroids: (22R,23R)-22,23-dihydroxy-3alpha-fluorostigmastan-6-one and (22R,23R)-22,23-dihydroxy-3beta-fluorostigmastan-6-one. Their bioactivities were evaluated in the rice lamina inclinat... |
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Synthesis and biological activity of furostanic analogues of brassinosteroids bearing the 5alpha-hydroxy-6-oxo moiety.
Steroids 72(14) , 955-9, (2007) Two furostanic analogues of brassinosteroids bearing the 5alpha-hydroxy-6-oxo moiety were synthesized and their biological activity studied using the bean second internode elongation test. One of the compounds produced significant stimulation at doses of 2.5 ... |
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Studies on steroidal plant-growth regulators (XVII)--a new synthesis of homobrassinolide and (22S, 23S)-22, 23-epi-homobrassinolide.
Sci. China,. Ser. B, Chem. Life Sci. Earth Sci. 34(6) , 706-11, (1991) Homobrassinolide (2) and (22S, 23S)-22,23-epi-homobrassinolide (4) were synthesized from stigmasterol in seven steps respectively in 4.7% and 24.1% overall yields. The ratio of 2 to 4 is 1:5. The key step is the highly regioselective formation of the B-homo-7... |
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Induction of hexokinase I expression in normal and diabetic rats by a brassinosteroid isoform.
Eur. J. Pharm. Sci. 41(1) , 1-9, (2010) This study aimed to investigate the effect of the plant growth regulator 28-homobrassinolide (HB) on the hexokinase I (HK I) enzyme gene expression in the tissues of normal and streptozotocin-induced diabetic rats. Normal and diabetic rats were administered 5... |
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Recent developments in the field of plant steroid hormones.
Lipids 32(12) , 1303-8, (1997) Brassinolide and related brassinosteroids are a novel group of steroids which appear to be ubiquitous in plants. There is compelling evidence, particularly from recent genetic studies, that these steroids are essential for normal plant growth and development.... |
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Toxicity of (22R,23R)-22,23-dihydroxystigmastane derivatives to cultured cancer cells.
Steroids 75(3) , 287-94, (2010) Toxicity of eight 22,23-dihydroxystigmastane derivatives (four pairs of (22R,23R)- and (22S,23S)-isomers differing in steroid backbone structure) to human breast carcinoma MCF-7 cells was compared. For every pair of structurally related compounds, (22R,23R) i... |
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A comparative study on the effect of homobrassinolide and gibberellic acid on lipid peroxidation and antioxidant status in normal and diabetic rats.
J. Enzyme Inhib. Med. Chem. 24(5) , 1122-7, (2009) Dietary content of phytohormones may potentially influence metabolic processes in animal cells. This study therefore aimed to investigate the effect of two plant growth regulators homobrassinolide (HB) and gibberellic acid (GBA) on the antioxidant defense sta... |
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Action of brassinosteroids on the epithelial cell line from Chironomus tentans.
Z. Naturforsch., C, J. Biosci. 47(3-4) , 280-4, (1992) The two brassinosteroids, 22 S,23 S-homobrassinolide and 22 S,23 S-homocastasterone are weak competitors of the binding of [3H]ponasterone A to the intracellular ecdysteroid receptor from the epithelial cell line from Chironomus tentans. The relative affiniti... |