met-leu-phe acetate salt
met-leu-phe acetate salt结构式
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常用名 | met-leu-phe acetate salt | 英文名 | met-leu-phe acetate salt |
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| CAS号 | 59881-08-2 | 分子量 | 409.54300 | |
| 密度 | 1.183 g/cm3 | 沸点 | 693.7ºC at 760 mmHg | |
| 分子式 | C20H31N3O4S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 373.3ºC |
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A novel peptide-grafted liposomal delivery system targeted to macrophages.
Antimicrob. Agents Chemother. 42(2) , 348-51, (1998) The interaction of chemotactic peptide (e.g., fMet-Leu-Phe)-grafted liposomes with macrophages is noted to be rapid and specific. At a grafted peptide concentration of 100 nmol, internalization of the peptide-grafted liposomes by the macrophages is found to r... |
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Band-selective carbonyl to aliphatic side chain 13C-13C distance measurements in U-13C,15N-labeled solid peptides by magic angle spinning NMR.
J. Am. Chem. Soc. 126(3) , 948-58, (2004) We describe three-dimensional magic angle spinning NMR experiments that enable simultaneous band-selective measurement of the multiple distance constraints between carbonyl and side chain carbons in uniformly 13C,15N-labeled peptides. The approaches are desig... |
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Arachidonic acid release in rabbit neutrophils.
Biochem. J. 257(3) , 633-7, (1989) [3H]Arachidonic acid is released after stimulation of rabbit neutrophils with fMet-Leu-Phe or platelet-activating factor (PAF). The release is rapid and dose-dependent, and is inhibited in phorbol 12-myristate 13-acetate (PMA)-treated rabbit neutrophils. The ... |
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Alpha-1-antichymotrypsin inhibits the NADPH oxidase-enzyme complex in phorbol ester-stimulated neutrophil membranes.
J. Immunol. 149(9) , 3059-65, (1992) The generation of superoxide anion and release of granule contents are essential to the bactericidal function of neutrophils, but may also contribute to host tissue damage during inflammation. In previous studies (J. Immunol. 146:2388), we have demonstrated t... |
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The interaction of 3,5-pyrazolidinedione drugs with receptors for f-Met-Leu-Phe on human neutrophil leukocytes: a study of the structure-activity relationship.
Can. J. Physiol. Pharmacol. 69(3) , 419-25, (1991) The 3,5-pyrazolidinedione (3,5-P) drugs, phenylbutazone and sulfinpyrazone, have been reported to bind to receptors for the chemotactic peptide, f-Met-Leu-Phe, and to behave as functional antagonists of f-Met-Leu-Phe in human and rabbit neutrophils. To explor... |
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Effect of cytotoxic drugs on mature neutrophil function in the presence and absence of granulocyte-macrophage colony-stimulating factor.
Br. J. Haematol. 84(2) , 316-21, (1993) The effects of the cytotoxic drugs, adriamycin, cyclophosphamide, daunomycin (daunorubicin), prednisolone, actinomycin D, azacytidine and vincristine at concentrations of 1 microM on mature neutrophil function were examined. Up to 5 h incubation with adriamyc... |
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Impaired chemotaxis and cell adhesion due to decrease in several cell-surface receptors in cathepsin E-deficient macrophages.
J. Biochem. 145(5) , 565-73, (2009) Cathepsin E is an endo-lysosomal aspartic proteinase exclusively present in immune system cells. Previous studies have shown that cathepsin E-deficient (CatE(-/-)) mice display aberrant immune responses such as atopic dermatitis and higher susceptibility to b... |
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The effects of interleukin-1 therapy on peripheral blood granulocyte function in humans.
Cancer Immunol. Immunother. 37(1) , 26-30, (1993) During a phase I trial of interleukin-1 alpha (IL-1 alpha) in patients with ovarian carcinomas, the effects of this treatment on blood granulocyte respiratory burst and locomotive responses were examined. Differences in baseline granulocyte function in patien... |
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Leucocyte activation by collagen-stimulated platelets in whole blood.
Scand. J. Clin. Lab. Invest. 62(6) , 451-61, (2002) Interaction between vascular cells plays an important role in the initial phases of the inflammatory process, but the mechanisms responsible for cell-cell communication are not fully understood. In this study, activation of leucocytes and platelets in heparin... |
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Desensitization by protein kinase C activation differentially uncouples formyl peptide receptors from effector enzymes in HL-60 granulocytes.
Cell. Signal. 5(6) , 735-45, (1993) The hypothesis that protein kinase C (PKC) participates in agonist-mediated desensitization of formyl peptide receptors in HL-60 granulocytes was tested. fMet-Leu-Phe and leukotriene B4(LTB4) produced homologous desensitization of agonist-stimulated intracell... |