8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤
8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤结构式
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常用名 | 8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤 | 英文名 | MMPX |
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| CAS号 | 78033-08-6 | 分子量 | 266.29600 | |
| 密度 | 1.249g/cm3 | 沸点 | 476.4ºC at 760 mmHg | |
| 分子式 | C12H18N4O3 | 熔点 | 189-190ºC | |
| MSDS | 中文版 美版 | 闪点 | 241.9ºC |
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In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease.
Nat. Commun. 6 , 6965, (2015) 3',5'-cyclic adenosine monophosphate (cAMP) is an ubiquitous second messenger that regulates physiological functions by acting in distinct subcellular microdomains. Although several targeted cAMP biosensors are developed and used in single cells, it is unclea... |
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Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta.
Biochem. Pharmacol. 38 , 3331, (1989) In this study three forms of cyclic nucleotide phosphodiesterase (PDE) isolated from rabbit aorta were pharmacologically characterized, and the consequence of selective inhibition of calmodulin-stimulated PDE (CaM-PDE) and cGMP specific PDE (cG-PDE) was evalu... |
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Methylxanthine inhibitors of phosphodiesterases.
Meth. Enzymol. 159 , 489, (1988)
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BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function.
Am. J. Physiol. Renal Physiol. 310 , F994-9, (2016) Large-conductance Ca(2+)-activated K(+) (BK) channels are critical regulators of detrusor smooth muscle (DSM) function. We aimed to investigate phosphodiesterase type 1 (PDE1) interactions with BK channels in human DSM to determine the mechanism by which PDE1... |