拉坦前列腺素(游离酸)
拉坦前列腺素(游离酸)结构式
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常用名 | 拉坦前列腺素(游离酸) | 英文名 | LatanoprostAcid |
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| CAS号 | 41639-83-2 | 分子量 | 390.513 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 609.1±50.0 °C at 760 mmHg | |
| 分子式 | C23H34O5 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 336.2±26.6 °C |
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New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance.
Eur. J. Pharm. Biopharm. 95 , 203-14, (2015) Latanoprost is a practically insoluble prostaglandin F2α analog considered a first-line agent for glaucoma treatment. From a pharmaceutical point of view, latanoprost is challenging to be formulated as an eye drop due to its poor water solubility and the pres... |
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Effect of prostaglandins A(2), E(1), F(2 alpha)and latanoprost on cultured human iridal melanocytes.
Exp. Eye Res. 70(1) , 113-20, (2000) The effect of various prostaglandins on the growth, melanogenesis and dendrification of cultured iridal melanocytes were studied. Iridal melanocytes were isolated and cultured with medium supplemented with cAMP elevating agents and basic fibroblast growth fac... |
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Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells.
Invest. Ophthalmol. Vis. Sci. 38(13) , 2772-80, (1997) To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle cells in vitro and to determine whether MMP release is altered by exposure to prostaglandins (PGs).Human ciliary smooth muscle cells were grown to confluence in monolayer cultures ... |
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Increased human scleral permeability with prostaglandin exposure.
Invest. Ophthalmol. Vis. Sci. 42(7) , 1514-21, (2001) To investigate the effect of prostaglandins (PGs) on the permeability of human sclera in vitro.Twenty-three pairs of human eye bank eyes were studied. Circular pieces of sclera were cultured in low-serum DMEM/F-12 media. Scleral hydration was assessed by meas... |
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Latanoprost and matrix metalloproteinase-1 in human choroid organ cultures.
Curr. Eye Res. 22(3) , 198-207, (2001) Latanoprost, a prostaglandin F2a analogue and ocular hypotensive agent, alters extracellular matrix and matrix metalloproteinases (MMPs), including MMP-1, within tissues of the uveoscleral outflow pathway. In addition to these tissues, the anterior choroid al... |
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Rapid metabolic responses to prostaglandins in cultured cells expressing the FP-receptor.
Adv. Exp. Med. Biol. 407 , 231-6, (1997)
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