N,N'-二甲基-9,9'-联吖啶鎓硝酸盐
N,N'-二甲基-9,9'-联吖啶鎓硝酸盐结构式
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常用名 | N,N'-二甲基-9,9'-联吖啶鎓硝酸盐 | 英文名 | Lucigenin |
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| CAS号 | 2315-97-1 | 分子量 | 510.497 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C28H22N4O6 | 熔点 | 250ºC | |
| MSDS | 美版 | 闪点 | N/A |
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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
Nature Chemistry 6(10) , 885-92, (2014) Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity ... |
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Trace detection of triphenylene by surface enhanced Raman spectroscopy using functionalized silver nanoparticles with bis-acridinium lucigenine.
Langmuir 26(10) , 6977-81, (2010) Surface enhanced raman scattering (SERS) of triphenylene (TP) has been recorded on Ag nanoparticles functionalized with the molecular assembler bis-acridinium lucigenine dication (LG) which approaches the adsorbate to the metal surface allowing for its detect... |
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Hollow Au/Ag nanostars displaying broad plasmonic resonance and high surface-enhanced Raman sensitivity.
Nanoscale 7 , 13629-37, (2015) Bimetallic Au/Ag hollow nanostar (HNS) nanoparticles with different morphologies were prepared in this work. These nanoplatforms were obtained by changing the experimental conditions (concentration of silver and chemical reductors, hydroxylamine and citrate) ... |
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Small-Anion Selective Transmembrane "Holes" Induced by an Antimicrobial Peptide Too Short to Span Membranes.
J. Phys. Chem. B 119 , 8553-60, (2015) Whereas many membrane-destabilization modes have been suggested for membrane-spanning antimicrobial peptides (AMPs), few are available for those too short to span membrane thickness. Here we show that ORB-1, a 15-residue disulfide-bridged AMP that is only ∼20... |
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Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(4) , R426-33, (2014) Exposing mice to a chronic hypoxic treatment (10% oxygen, 21 days) that promotes pulmonary hypertension was observed to attenuate the pulmonary vasoconstriction response to acute hypoxia (HPV) both in vivo and in isolated pulmonary arteries. Since catalase re... |
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Eupafolin inhibits PGE2 production and COX2 expression in LPS-stimulated human dermal fibroblasts by blocking JNK/AP-1 and Nox2/p47(phox) pathway.
Toxicol. Appl. Pharmacol. 279(2) , 240-51, (2014) Eupafolin, a major active component found in the methanol extracts of Phyla nodiflora, has been used to treat inflammation of skin. We examined its effects on cyclooxygenase-2 (COX-2) expression in LPS-treated human dermal fibroblasts. Lipopolysaccharide (LPS... |
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The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke.
Free Radic. Biol. Med. 77 , 168-82, (2014) The contribution of oxidative stress to ischemic brain damage is well established. Nevertheless, for unknown reasons, several clinically tested antioxidant therapies have failed to show benefits in human stroke. Based on our previous in vitro work, we hypothe... |
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p47phox and reactive oxygen species production modulate expression of microRNA-451 in macrophages.
Free Radic. Res. 49(1) , 25-34, (2014) The production of microRNAs (miRNA) is influenced by various stimuli, including environmental stresses. We hypothesized that reactive oxygen species (ROS)-associated stress could regulate macrophage miRNA synthesis. miRNAs undergo unique steps of maturation p... |
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Resveratrol and sildenafil synergistically improve diabetes-associated erectile dysfunction in streptozotocin-induced diabetic rats.
Life Sci. 135 , 43-8, (2015) Despite effective control of blood glucose levels in diabetic patients, complaints of diabetes-associated erectile dysfunction (ED) persist. Resveratrol has been indicated to possess anti-diabetic effects and therapeutic potential for ED. This study was condu... |
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A new method for the quantification of superoxide dismutase mimics with an allopurinol-xanthine oxidase-lucigenin enhanced system.
J. Biol. Inorg. Chem. 16 , 753-761, (2011) Allopurinol is a prodrug converted to oxypurinol by xanthine oxidase, a process followed by an efficient enzyme inhibition. Using a lucigenin-enhanced chemiluminescence method, we found that, under alkaline conditions, superoxide radicals are produced in larg... |