Irosustat
Irosustat结构式
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常用名 | Irosustat | 英文名 | STX64 |
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| CAS号 | 288628-05-7 | 分子量 | 309.33800 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C14H15NO5S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Evidence of estrone-sulfate uptake modification in young and middle-aged rat prostate.
J. Steroid Biochem. Mol. Biol. 152 , 89-100, (2015) High plasma exposure to estrogens is often associated with prostate cancer. Reducing this phenomenon may present therapeutic benefits. The involvement of estrone sulphate (E1S), the most abundant circulating estrogen in men, has been partially studied in this... |
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Anti-tumor effect of Shu-Gan-Liang-Xue decoction in breast cancer is related to the inhibition of aromatase and steroid sulfatase expression.
J. Ethnopharmacol. 154(3) , 687-95, (2014) Shu-Gan-Liang-Xue Decoction (SGLXD), a traditional Chinese herbal formula used to ameliorate the hot flushes in breast cancer patients, was reported to have anti-tumor effect on breast cancer. Estrogen plays a critical role in the genesis and evolution of bre... |
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Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease.
J. Hepatol. 64 , 44-52, (2015) Chronic inflammatory liver diseases are associated with estrogen excess and feminization in men, which is thought to be due to compromised liver function to break down estrogens. The goal of this study is to determine whether the inflammatory induction of ste... |