3-氯-L-酪氨酸
3-氯-L-酪氨酸结构式
|
常用名 | 3-氯-L-酪氨酸 | 英文名 | 3-Chloro-L-tyrosine |
|---|---|---|---|---|
| CAS号 | 7423-93-0 | 分子量 | 215.634 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 388.6±42.0 °C at 760 mmHg | |
| 分子式 | C9H10ClNO3 | 熔点 | 249ºC | |
| MSDS | 中文版 美版 | 闪点 | 188.8±27.9 °C |
|
Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.
J. Proteome Res. 13(7) , 3455-66, (2014) A subgroup of obese individuals, referred to as metabolically healthy obese (MHO), have preserved insulin sensitivity and a normal lipid profile despite being obese. The molecular basis for this improved cardiometabolic profile remains unclear. Our objective ... |
|
|
Protein stabilization utilizing a redefined codon.
Sci. Rep. 5 , 9762, (2015) Recent advances have fundamentally changed the ways in which synthetic amino acids are incorporated into proteins, enabling their efficient and multiple-site incorporation, in addition to the 20 canonical amino acids. This development provides opportunities f... |
|
|
Syntheses of halogen derivatives of L-tryptophan, L-tyrosine and L-phenylalanine labeled with hydrogen isotopes.
J. Labelled Comp. Radiopharm. 59 , 08-Apr, (2016) Halogenated, labeled with tritium and doubly with deuterium and tritium, derivatives of L-tryptophan, i.e. 5'-bromo-[2-(3)H]-, 5'-bromo-[2-(2)H/(3)H]-, 5'-fluoro-[2-(3)H]-5'-fluoro-[2-(2)H/(3)H]-, 6'-fluoro-[2-(3)H]-, 6'-fluoro-[2-(2)H/(3)H]-L-tryptophan, as ... |
|
|
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
J. Am. Coll. Cardiol. 49(20) , 1993-2000, (2007) This study investigated relationships between plasma myeloperoxidase (MPO), protein oxidation markers, and clinical outcome retrospectively in patients after acute myocardial infarction (MI).Reactive oxidants are implicated in cardiovascular disease, and elev... |
|
|
A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine.
J. Chromatogr. A. 1217 , 3269-3274, (2010) Oxidative stress has been implicated in various pathologies as well as in environmental pollutant-induced negative health outcomes. In this work we have developed an analytical method to measure oxidative stress markers namely m-, o-tyrosine, 3-chlorotyrosine... |
|
|
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease.
Proc. Natl. Acad. Sci. U. S. A. 110(26) , E2332-41, (2013) Inflammatory bowel disease (IBD) arises from inappropriate activation of the mucosal immune system resulting in a state of chronic inflammation with causal links to colon cancer. Helicobacter hepaticus-infected Rag2(-/-) mice emulate many aspects of human IBD... |
|
|
Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.
Basic Res. Cardiol. 104(3) , 307-20, (2009) Increased oxidative stress has been implicated in the pathogenesis of a number of cardiovascular diseases. Recent findings suggest that myeloperoxidase (MPO) may play a key role in the initiation and maintenance of chronic heart failure (CHF) by contributing ... |
|
|
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.
Ann. Rheum. Dis. 72(10) , 1725-31, (2013) Phagocyte-derived myeloperoxidase (MPO) and pro-inflammatory high density lipoprotein (HDL) associate with rheumatoid arthritis (RA), but the link between MPO and HDL has not been systematically examined. In this study, we investigated whether MPO can oxidise... |
|
|
Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction.
Clin. Biochem. 41(7-8) , 554-60, (2008) Inflammation, a major risk factor for acute myocardial infarction (AMI), is associated with leukocytic activation, secretion of myeloperoxidase (MPO) and generation of the oxidative damage marker, 3-chlorotyrosine (3-Cl-Tyr). To study their association with A... |
|
|
Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins.
Proteomics 9(6) , 1617-31, (2009) Protein oxidation is thought to contribute to a number of inflammatory diseases, hence the development of sensitive and specific analytical techniques to detect oxidative PTMs (oxPTMs) in biological samples is highly desirable. Precursor ion scanning for frag... |