D-肌醇1,3,4-三磷酸铵盐
D-肌醇1,3,4-三磷酸铵盐结构式
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常用名 | D-肌醇1,3,4-三磷酸铵盐 | 英文名 | D-MYO-INOSITOL 1,3,4-TRIS-PHOSPHATE AMMONIUM SALT |
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| CAS号 | 93133-76-7 | 分子量 | 432.51200 | |
| 密度 | 2.25g/cm3 | 沸点 | 877.6ºC at 760 mmHg | |
| 分子式 | C26H28N2O4 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 484.5ºC |
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Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.
J. Biol. Chem. 274(27) , 18973-80, (1999) Ca2+-activated Cl- channels are inhibited by inositol 3,4,5, 6-tetrakisphosphate (Ins(3,4,5,6)P4) (Xie, W., Kaetzel, M. A., Bruzik, K. S., Dedman, J. R., Shears, S. B., and Nelson, D. J. (1996) J. Biol. Chem. 271, 14092-14097), a novel second messenger that i... |
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Characterization of an inositol 1,3,4-trisphosphate 5/6-kinase gene that is essential for drought and salt stress responses in rice.
Plant Mol. Biol. 77(6) , 547-63, (2011) Drought and salt stresses are major limiting factors for crop production. To identify critical genes for stress resistance in rice (Oryza sativa L.), we screened T-DNA mutants and identified a drought- and salt-hypersensitive mutant dsm3. The mutant phenotype... |
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Properties of the inositol 3,4,5,6-tetrakisphosphate 1-kinase purified from rat liver. Regulation of enzyme activity by inositol 1,3,4-trisphosphate.
J. Biol. Chem. 272(4) , 2285-90, (1997) Inositol 3,4,5,6-tetrakisphosphate is a novel intracellular signal that regulates calcium-dependent chloride conductance (Xie, W., Kaetzel, M. A., Bruzik, K. S., Dedman, J. R., Shears, S. B., and Nelson, D. J. (1996) J. Biol. Chem. 271, 14092-14097). The mole... |
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Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C.
Dev. Biol. 302(1) , 143-53, (2007) Integrin signaling modulates trophoblast adhesion to extracellular matrices during blastocyst implantation. Fibronectin (FN)-binding activity on the apical surface of trophoblast cells is strengthened after elevation of intracellular Ca(2+) downstream of inte... |
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Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase.
Biochem. Biophys. Res. Commun. 232(3) , 678-81, (1997) We have sequenced and recombinantly expressed as a fusion protein an expressed sequence tag clone (GB Z25963) from Arabidopsis thaliana that represents the plant homologue of human inositol 1,3,4 trisphosphate 5/6-kinase. The 1365 base pair clone has an open ... |
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A membrane-permeant, bioactivatable derivative of Ins(1,3,4)P3 and its effect on Cl(-)-secretion from T84 cells.
Bioorg. Med. Chem. Lett. 8(14) , 1857-60, (1998) The synthesis of rac-2,5,6-tri-O-butyryl-myo-inositol 1,3,4-trisphosphate hexakis(acetoxymethyl) ester [Bt3-Ins(1,3,4)P3/AM, 1], a membrane-permeant derivative of myo-inositol 1,3,4-trisphosphate [Ins(1,3,4)P3] is reported. 1 inhibited calcium-mediated chlori... |
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Smooth muscle aldolase C-bound inositol 1,4,5-trisphosphate studied in vitro under physiological conditions.
Biochim. Biophys. Acta 1401(1) , 81-92, (1998) Our goal was to quantitate inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) binding to aldolase C tetramer (aldolase4) and its displacement by inositol 1,3,4-trisphosphate (Ins(1,3,4)P3) under conditions which approximated the in vivo state. Anions were found to h... |
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Characterization of a functional AT1A angiotensin receptor in pancreatoma AR4-2J cells.
Peptides 20(7) , 829-36, (1999) Functional angiotensin receptors were characterized in the rat pancreatic acinar cell line AR4-2J. Angiotensin II stimulated a dose-dependent release of amylase and production of inositol phosphates. Results of high-performance liquid chromatography separatio... |
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Selectivity in inositol phosphate production following pancreatic acinar cell desensitization.
Biochem. Biophys. Res. Commun. 206(3) , 870-7, (1995) The effects of pancreatic acinar cell desensitization by carbamylcholine (Cch), caerulein (Cae) and the phorbol ester TPA on the production of inositol tris and tetrakisphosphates were studied. In control acini, Cch and Cae caused comparable increases in Ins ... |
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Oxytocin-stimulated insulin release in a clonal beta-cell line RINm5F: involvement of phospholipase C-dependent and -independent pathways.
Zhongguo Yao Li Xue Bao 17(5) , 390-4, (1996) To study the mechanisms underlying oxytocin (Oxy)-induced insulin release.In a clonal pancreatic beta-cell line, RINm5F cells.Oxy increased insulin release and [Ca2+]i in a concentration-dependent manner. Oxy-induced insulin release was not altered by pretrea... |