甘氨酰甘氨酰-L-组氨酸
甘氨酰甘氨酰-L-组氨酸结构式
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常用名 | 甘氨酰甘氨酰-L-组氨酸 | 英文名 | Gly-Gly-His |
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| CAS号 | 7451-76-5 | 分子量 | 269.25700 | |
| 密度 | 1.44 | 沸点 | N/A | |
| 分子式 | C10H15N5O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Copper.Lys-Gly-His-Lys mediated cleavage of tRNA(Phe): studies of reaction mechanism and cleavage specificity.
J. Inorg. Biochem. 103 , 871-875, (2009) The reactivity of [Cu2+.Lys-Gly-His-Lys-NH2]2+ and [Cu2+.Lys-Gly-His-Lys]+ toward tRNA(Phe) has been evaluated. The amidated and carboxylate forms of the copper peptides display complex binding behavior with strong and weak sites evident (K(D1)(app) approxima... |
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Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts.
Acta Pol. Pharm. 69(6) , 1303-6, (2012) Cosmeceuticals represent a marriage between cosmetics and pharmaceuticals. There are numerous cosmeceutically active products which can be broadly classified into the following categories: antioxidants, oligopeptides, growth factors and pigment lightning agen... |
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Highly specific oxidative cross-linking of proteins mediated by a nickel-peptide complex.
Biochemistry 34(14) , 4733-9, (1995) The Ni(II) complex of the tripeptide NH2-Gly-Gly-His-COOH is shown to mediate efficient protein-protein cross-linking in the presence of oxidants such as oxone and monoperoxyphthalic acid. Only proteins that associate specifically in solution are cross-linked... |
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Diastereoselective DNA cleavage recognition by Ni(II) x Gly-Gly-His-derived metallopeptides.
J. Am. Chem. Soc. 128(10) , 3198-207, (2006) Site-selective DNA cleavage by diastereoisomers of Ni(II) x Gly-Gly-His-derived metallopeptides was investigated through high-resolution gel analyses and molecular dynamics simulations. Ni(II) x L-Arg-Gly-His and Ni(II) x D-Arg-Gly-His (and their respective L... |
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Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides.
Arch. Biochem. Biophys. 299(1) , 154-62, (1992) The generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of several oligopeptides was investigated by electron spin resonance (ESR) utilizing 5,5-dimethyl-1-pyrroline N-oxide (DMPO) as a spin trap. Incubation of Ni2+ with cumene hydro... |
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Protein cross-linking mediated by metal ion complexes.
Met. Ions Biol. Syst. 38 , 351-84, (2001)
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Determining protein-protein interactions by oxidative cross-linking of a glycine-glycine-histidine fusion protein.
Biochemistry 37(13) , 4397-406, (1998) The Ni(II) complex of the tripeptide NH2-glycine-glycine-histidine-COOH (GGH) mediates efficient protein-protein cross-linking in the presence of oxidants such as oxone and monoperoxyphthalic acid (MMPP). Here we demonstrate that GGH fused to the amino termin... |
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Nickel(III) oxidation of its glycylglycylhistamine complex.
Dalton Trans. (21) , 3508-14, (2004) The doubly-deprotonated Ni(III) complex of Gly(2)Ha (where Ha is histamine) undergoes base-assisted oxidative self-decomposition of the peptide. At |
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Design, synthesis and DNA-cleavage of Gly-Gly-His-naphthalene diimide conjugates.
Bioorg. Med. Chem. Lett. 9(20) , 2935-40, (1999) Naphthalene diimides with one and two metal-chelating Gly-Gly-His (GGH) motifs have been synthesized. Both conjugates induce single-stranded cleavage of plasmid pBR322 DNA in the presence of nickel and Oxone and are approximately 100-fold more efficient than ... |
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DNA-fiber EPR investigation of the influence of amino-terminal residue stereochemistry on the DNA binding orientation of Cu(II).Gly-Gly-His-derived metallopeptides.
J. Inorg. Biochem. 101(10) , 1529-36, (2007) DNA fiber EPR was used to investigate the DNA binding stabilities and orientations of Cu(II).Gly-Gly-His-derived metallopeptides containing D- vs. L-amino acid substitutions in the first peptide position. This examination included studies of Cu(II).D-Arg-Gly-... |