![]() N-叔丁氧羰基羟胺结构式
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常用名 | N-叔丁氧羰基羟胺 | 英文名 | tert-Butyl hydroxycarbamate |
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CAS号 | 36016-38-3 | 分子量 | 133.146 | |
密度 | 1.1±0.1 g/cm3 | 沸点 | 250.4±9.0 °C at 760 mmHg | |
分子式 | C5H11NO3 | 熔点 | 53-55 °C(lit.) | |
MSDS | 中文版 美版 | 闪点 | 105.2±18.7 °C |
N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.
J. Med. Chem. 54 , 6843-58, (2011) The discovery, syntheses, and structure-activity relationships (SAR) of a new family of heterocyclic antibacterial compounds based on N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds are described. A structurally diverse library of ∼100 heterocyclic molecules ... |
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Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase.
J. Med. Chem. 35 , 3648, (1992) In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds were bioactivated by O-demethylation to release nitroxyl (HN ... |
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Reactions of nitroso hetero-Diels-Alder cycloadducts with azides: stereoselective formation of triazolines and aziridines.
J. Org. Chem. 72 , 3929, (2007) The addition of azides to acylnitroso hetero-Diels-Alder cycloadducts derived from cyclopentadiene affords exo-triazolines in excellent yield. The reaction is greatly affected by the level of alkene strain, while sterically demanding azides do not hinder the ... |
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D.S. Jones et al.
Tetrahedron Lett. 41 , 1531, (2000)
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M. Adamczyk, R.E. Reddy
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Tetrahedron Lett. 33 , 5055, (1992)
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Tetrahedron Lett. 42 , 5897, (2001)
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Tetrahedron Lett. 33 , 5055, (1992)
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Synth. Commun. 22 , 2579, (1992)
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Useful hydroxylamine derivatives for the synthesis of hydroxamic acids.
Tetrahedron Lett. 33(35) , 5055-5058, (1992)
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