醛试剂
醛试剂结构式
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常用名 | 醛试剂 | 英文名 | Dimedone |
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| CAS号 | 126-81-8 | 分子量 | 140.18 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 233.7±23.0 °C at 760 mmHg | |
| 分子式 | C8H12O2 | 熔点 | 146-148 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 85.1±19.6 °C |
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[The role of aldehydes in development of oxidative stress under rhabdomyolysis in rats].
Fiziol. Zh. 59(1) , 25-31, (2013) We investigated the changes in the forms of plasma iron and participation of aldehydes in the development of oxidative stress under glycerol-induced rhabdomyolysis in rats. Rhabdomyolysis was caused by intramuscular injection of 50% glycerol in the dose 10 ml... |
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Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
FEBS J. 280(23) , 6150-61, (2013) Cellular exposure to reactive oxygen species induces rapid oxidation of DNA, proteins, lipids and other biomolecules. At the proteome level, cysteine thiol oxidation is a prominent post-translational process that is implicated in normal physiology and numerou... |
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Open season for hunting and trapping post-translational cysteine modifications in proteins and enzymes.
ChemBioChem. 12(6) , 841-4, (2011)
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"Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen-presenting cells.
J. Pharmacol. Exp. Ther. 331(2) , 372-81, (2009) Antigen-presenting cells (APC) are thought to play an important role in the pathogenesis of drug-induced immune reactions. Various pathological factors can activate APC and therefore influence the immune equilibrium. It is interesting that several diseases ha... |
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Formation and reactions of sulfenic acid in human serum albumin.
Meth. Enzymol. 473 , 117-36, (2010) Protein sulfenic acids (R-SOH) are receiving increased interest as intermediates in redox processes. Human serum albumin, the most abundant protein in plasma, possesses a single free thiol. We describe herein the different methodologies that we have employed ... |
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Reactivity of sulfenic acid in human serum albumin.
Biochemistry 47(1) , 358-67, (2008) Sulfenic acid is formed upon oxidation of thiols and is a central intermediate in the redox modulation of an increasing number of proteins. Methods for quantifying or even detecting sulfenic acid are scarce. Herein, the reagent 7-chloro-4-nitrobenz-2-oxa-1,3-... |
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The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation.
Eur. J. Immunol. 42(8) , 2152-64, (2012) B-cell receptor (BCR) ligation generates reactive oxygen intermediates (ROIs) that play a role in cellular responses. Although ROIs can oxidize all macromolecules, it was unclear which modifications control B-cell responses. In this study, we demonstrate the ... |
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Sphaeropsidones, phytotoxic dimedone methyl ethers produced by Diplodia cupressi: a structure-activity relationship study.
J. Nat. Prod. 74(4) , 757-63, (2011) Sphaeropsidone and episphaeropsidone are two phytotoxic dimedone methyl ethers produced by Diplodia cupressi, the causal agent of a canker disease of cypress in the Mediterranean area. In this study, eight derivatives obtained by chemical modifications and tw... |
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Contemporary techniques for detecting and identifying proteins susceptible to reversible thiol oxidation.
Biochem. Soc. Trans. 39(5) , 1260-7, (2011) Elevated protein oxidation is a widely reported hallmark of most major diseases. Historically, this 'oxidative stress' has been considered causatively detrimental, as the protein oxidation events were interpreted simply as damage. However, recent advances hav... |
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Putative denitrosylase activity of Cu,Zn-superoxide dismutase.
Free Radic. Biol. Med. 43(5) , 830-6, (2007) The Cu,Zn-superoxide dismutase (SOD1) has been reported to exert an S-nitrosylated glutathione (GSNO) denitrosylase activity that was augmented by a familial amyotrophic lateral sclerosis (FALS)-associated mutation in this enzyme. This putative enzymatic acti... |