N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine结构式
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常用名 | N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine | 英文名 | N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine |
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| CAS号 | 103974-29-4 | 分子量 | 220.24600 | |
| 密度 | 1.335g/cm3 | 沸点 | N/A | |
| 分子式 | C7H12N2O4S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Biological monitoring of workers exposed to N-N-dimethylformamide. II. Dimethylformamide and its metabolites in urine of exposed workers.
Int. Arch. Occup. Environ. Health 67(1) , 47-52, (1995) N,N-Dimethylformamide (DMF) exposure was monitored in a synthetic leather factory; at the same time, urinary dimethylformamide and its metabolites were measured in urine samples collected before and at the end of workshifts. The study was run during two diffe... |
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Mitochondrial DNA alterations in blood of the humans exposed to N,N-dimethylformamide.
Chem. Biol. Interact. 165(3) , 211-9, (2007) N,N-Dimethylformamide (DMF) has been widely used in industries because of its extensive miscibility with water and solvents. Its health effects include hepatotoxicity and male reproductoxicity, possibly linked with mitochondrial DNA (mtDNA) alterations includ... |
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N-methylcarbamoyl adducts at the N-terminal valine of globin in workers exposed to N,N-dimethylformamide.
Arch. Toxicol. 72(5) , 309-13, (1998) N,N-dimethylformamide (DMF) is a commonly used industrial solvent. The formation of some metabolites of DMF in humans occurs via N-methyl-carbamoylated species (e.g. N-methylcarbamoylated glutathione). The aim of our study was to investigate whether DMF leads... |
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Analysis of urinary N-acetyl-S-(N-methylcarbamoyl)cysteine, the mercapturic acid derived from N,N-dimethylformamide.
J. Chromatogr. B. Biomed. Sci. Appl. 759(2) , 349-54, (2001) Human biotransformation of the industrial solvent N,N-dimethylformamide gives raise to N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) which has the longest half-life (about 23 h) among urinary metabolites of N,N-dimethylformamide. It could be used for monitori... |
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Biological monitoring of workers exposed to N, N-dimethylfomamide. I. Methods of analysis.
Int. Arch. Occup. Environ. Health 67(1) , 41-6, (1995) Some methods for analysing N,N-dimethylformamide and its metabolites [hydroxymethyl-N-methylformamide, hydroxymethylformamide and N-acetyl-S-(N-methylcarbamoyl)cysteine] in the urine of exposed workers are described. Unchanged dimethylformamide was measured a... |
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Determination of N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) in the general population using gas chromatography-mass spectrometry.
J. Environ. Monit. 1(5) , 465-9, (1999) Carbamoylation of glutathione, peptides and DNA is thought to be one of the most important reactions occurring in an organism after exposure to nitrosoureas, methylformamides or isocyanates. The carcinogenic effects of carbamoylation are not yet fully clarifi... |
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The use of biomarkers of exposure of N,N-dimethylformamide in health risk assessment and occupational hygiene in the polyacrylic fibre industry.
Occup. Environ. Med. 62(5) , 330-6, (2005) N,N-dimethylformamide (DMF) was recently prioritised for field studies by the National Toxicology Program based on the potency of its reproductive toxic effects.To measure accurately exposure to DMF in occupational settings.In 35 healthy workers employed in t... |
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Urinary determination of N-acetyl- S-( N-methylcarbamoyl)cysteine and N-methylformamide in workers exposed to N, N-dimethylformamide.
Int. Arch. Occup. Environ. Health 75(7) , 445-52, (2002) We conducted this biomonitoring study with the aim of evaluating the correlation between the excretion of N-methylformamide (NMF) (mainly from N-hydroxy- N-methylformamide) and N-acetyl- S-( N-methylcarbamoyl)cysteine (AMCC), and levels of exposure to N, N-di... |
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Analysis of metabolites of N,N-dimethylformamide in urine samples.
Int. Arch. Occup. Environ. Health 77(6) , 427-32, (2004) To assess the suitability of different methods for biological monitoring of internal dose to N,N-dimethylformamide (DMF) in occupational settings.The determination of urinary metabolites of DMF, N-hydroxymethyl- N-methylformamide (HMMF), N-methylformamide (NM... |
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Biological monitoring of workers exposed to N, N-dimethylformamide in synthetic leather manufacturing factories in Korea.
Int. Arch. Occup. Environ. Health 77(2) , 108-12, (2004) To investigate the relationship between N, N-dimethylformamide (DMF) exposure and excretion of urinary N-acetyl- S-( N-methylcarbamoyl)cysteine (AMCC) and N-methylformamide (NMF) in workers at synthetic leather manufacturing factories in Korea, for the first ... |