1,2-二芥酰基-sn-甘油-3-磷酰胆碱
1,2-二芥酰基-sn-甘油-3-磷酰胆碱结构式
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常用名 | 1,2-二芥酰基-sn-甘油-3-磷酰胆碱 | 英文名 | 1,2-Dierucoyl-sn-glycero-3-PC |
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| CAS号 | 51779-95-4 | 分子量 | 898.33 | |
| 密度 | N/A | 沸点 | 480 °C | |
| 分子式 | C52H100NO8P | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Bilayer Effects of Antimalarial Compounds.
PLoS ONE 10 , e0142401, (2015) Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested the 80 most potent compounds from the box for bilayer-mediat... |
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Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.
PLoS ONE 8 , e68942, (2013) Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb strains that cannot control intrabacterial pH (pHIB) in an a... |
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Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.
J. Gen. Physiol. 138(2) , 249-70, (2011) The thiazolidinediones (TZDs) are used in the treatment of diabetes mellitus type 2. Their canonical effects are mediated by activation of the peroxisome proliferator-activated receptor γ (PPARγ) transcription factor. In addition to effects mediated by gene a... |
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Interaction of lipids with the neurotensin receptor 1.
Biochim. Biophys. Acta 1858 , 1278-87, (2016) Information about lipid-protein interactions for G protein-coupled receptors (GPCRs) is scarce. Here, we use electron spin resonance (ESR) and spin-labelled lipids to study lipid interactions with the rat neurotensin receptor 1 (NTS1). A fusion protein contai... |
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Studying antibiotic-membrane interactions via X-ray diffraction and fluorescence microscopy.
FEBS Open Bio 5 , 515-21, (2015) Antibiotic drug resistance is a serious issue for the treatment of bacterial infection. Understanding the resistance to antibiotics is a key issue for developing new drugs. We used penicillin and sulbactam as model antibiotics to study their interaction with ... |
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Structural determinants of water permeability through the lipid membrane.
J. Gen. Physiol. 131 , 69-76, (2008) Despite intense study over many years, the mechanisms by which water and small nonelectrolytes cross lipid bilayers remain unclear. While prior studies of permeability through membranes have focused on solute characteristics, such as size, polarity, and parti... |