L-Cystine

Names

[ CAS No. ]:
56-89-3

[ Name ]:
L-Cystine

[Synonym ]:
L-Dicysteine
(CYS)2
L-CYTISINE
CYSTINE, L-
L-Cystine (9CI)
(R,R)-3,3'-Dithiobis(2-aminopropionicacid)
oxidized L-cysteine
Acide (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoïque)
[3H]-Cystine
Cystine, L- (8CI)
Dicysteine
L-Cystine
cystine
L-(-)-Cystine
(2R,2'R)-3,3'-Disulfanediylbis(2-aminopropansäure)
Cystin
Cystine (L)-
1-cystine
Nephrin
(-)-Cystine
(H-Cys-OH)2
(R,R)-cystine
EINECS 200-296-3
l-cystin
h-(cys)
.β.,.β.'-Diamino-.β.,.β.'-dicarboxydiethyl disulfide
MFCD00064228
Acetylcysteine Impurity 1

Biological Activity

[Description]:

L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Ohtsu I, et al. Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. PLoS One. 2015 Apr 2;10(3):e0120619.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
468.2±45.0 °C at 760 mmHg

[ Melting Point ]:
260-261ºC

[ Molecular Formula ]:
C₆H₁₂N₂O₄S₂

[ Molecular Weight ]:
240.301

[ Flash Point ]:
237.0±28.7 °C

[ Exact Mass ]:
240.023849

[ PSA ]:
177.24000

[ LogP ]:
1.23

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.653

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HA2690000

CHEMICAL NAME :: Cystine, L-

CAS REGISTRY NUMBER :: 56-89-3

BEILSTEIN REFERENCE NO. :: 1728094

LAST UPDATED :: 199707

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H12-N2-O4-S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,199,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 279 gm/kg/93D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - death

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,199,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83262 No. of Facilities: 138 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 6186 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83262 No. of Facilities: 692 (estimated) No. of Industries: 5 No. of Occupations: 17 No. of Employees: 15248 (estimated) No. of Female Employees: 13345 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
HA2690000

[ Packaging Group ]:
III

[ HS Code ]:
2930901000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930901000

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