L-Cystine

Modify Date: 2024-01-01 18:33:41

L-Cystine Structure
L-Cystine structure
Common Name L-Cystine
CAS Number 56-89-3 Molecular Weight 240.301
Density 1.6±0.1 g/cm3 Boiling Point 468.2±45.0 °C at 760 mmHg
Molecular Formula C6H12N2O4S2 Melting Point 260-261ºC
MSDS Chinese USA Flash Point 237.0±28.7 °C

 Use of L-Cystine


L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.

 Names

Name L-cystine
Synonym More Synonyms

 L-Cystine Biological Activity

Description L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Ohtsu I, et al. Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. PLoS One. 2015 Apr 2;10(3):e0120619.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 468.2±45.0 °C at 760 mmHg
Melting Point 260-261ºC
Molecular Formula C6H12N2O4S2
Molecular Weight 240.301
Flash Point 237.0±28.7 °C
Exact Mass 240.023849
PSA 177.24000
LogP 1.23
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.653

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA2690000
CHEMICAL NAME :
Cystine, L-
CAS REGISTRY NUMBER :
56-89-3
BEILSTEIN REFERENCE NO. :
1728094
LAST UPDATED :
199707
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H12-N2-O4-S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
25 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,199,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
279 gm/kg/93D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - death
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,199,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83262 No. of Facilities: 138 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 6186 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83262 No. of Facilities: 692 (estimated) No. of Industries: 5 No. of Occupations: 17 No. of Employees: 15248 (estimated) No. of Female Employees: 13345 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS HA2690000
Packaging Group III
HS Code 2930901000

 Synthetic Route

 Customs

HS Code 2930901000

 Articles168

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FEBS J. 282(7) , 1214-24, (2015)

The crystal structures of carboxypeptidase T (CpT) complexes with phenylalanine and arginine substrate analogs - benzylsuccinic acid and (2-guanidinoethylmercapto)succinic acid - were determined by th...

In vitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican.

FEBS J. 280(12) , 2870-87, (2013)

Previously, we have shown that a proportion of the matrix metalloproteinase-9 (MMP-9) synthesized by the macrophage cell line THP-1 binds to a chondroitin sulfate proteoglycan (CSPG) core protein to f...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m...

 Synonyms

L-Dicysteine
(CYS)2
L-CYTISINE
CYSTINE, L-
L-Cystine (9CI)
(R,R)-3,3'-Dithiobis(2-aminopropionicacid)
oxidized L-cysteine
Acide (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoïque)
[3H]-Cystine
Cystine, L- (8CI)
Dicysteine
L-Cystine
cystine
L-(-)-Cystine
(2R,2'R)-3,3'-Disulfanediylbis(2-aminopropansäure)
Cystin
Cystine (L)-
1-cystine
Nephrin
(-)-Cystine
(H-Cys-OH)2
(R,R)-cystine
EINECS 200-296-3
l-cystin
h-(cys)
.β.,.β.'-Diamino-.β.,.β.'-dicarboxydiethyl disulfide
MFCD00064228
Acetylcysteine Impurity 1
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