Moclobemide N-Oxide

Modify Date: 2024-01-15 09:54:51

Moclobemide N-Oxide structure	Common Name	Moclobemide N-Oxide
	CAS Number	64544-24-7	Molecular Weight	284.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₇ClN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Moclobemide N-Oxide

Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm[1][2].

Name	Moclobemide N-Oxide
Synonym	More Synonyms

Description	Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	MAO-A
References	[1]. Rakic Ignjatovic A, et al. Moclobemide monotherapy vs. combined therapy with valproic acid or carbamazepine in depressive patients: a pharmacokinetic interaction study. Br J Clin Pharmacol. 2009 Feb;67(2):199-208. [2]. Geschke R, et al. Determination of the new monoamine oxidase inhibitor moclobemide and three of its metabolites in biological fluids by high-performance liquid chromatography. J Chromatogr. 1987 Sep 4;420(1):111-20.

Molecular Formula	C₁₃H₁₇ClN₂O₃
Molecular Weight	284.74
Exact Mass	284.092773
LogP	-0.10

Ro 12-5637

4-Chloro-N-[2-(4-oxido-4-morpholinyl)ethyl]benzamide

Benzamide, 4-chloro-N-[2-(4-oxido-4-morpholinyl)ethyl]-

4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide N-Oxide

Moclobemide N-Oxide

Use of Moclobemide N-Oxide

Names

Moclobemide N-Oxide Biological Activity

Chemical & Physical Properties

Synonyms