Bromoacetamido-PEG5-DOTA

Modify Date: 2024-01-27 08:25:40

Bromoacetamido-PEG5-DOTA structure	Common Name	Bromoacetamido-PEG5-DOTA
	CAS Number	2353410-19-0	Molecular Weight	787.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₅₅BrN₆O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bromoacetamido-PEG5-DOTA

Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bromoacetamido-PEG5-DOTA

Description	Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₀H₅₅BrN₆O₁₃
Molecular Weight	787.69