1698019-89-4

1698019-89-4 structure

Name: Bromoacetamido-PEG8-acid
Chemical Name: Bromoacetamido-PEG8- acid
CAS Number: 1698019-89-4
Molecular Formula: C₂₁H₄₀BrNO₁₁
Molecular Weight: 562.446
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-21 14:03:40
Modify Date: 2025-08-26 17:48:47
Bromoacetamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bromoacetamido-PEG8- acid
Synonyms	6,9,12,15,18,21,24,27-Octaoxa-3-azatriacontan-30-oic acid, 1-bromo-2-oxo- 1-Bromo-2-oxo-6,9,12,15,18,21,24,27-octaoxa-3-azatriacontan-30-oic acid MFCD27635172

Description	Bromoacetamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562