Bromoacetamido-PEG5-azide

Modify Date: 2024-01-08 20:05:06

Bromoacetamido-PEG5-azide Structure
Bromoacetamido-PEG5-azide structure
Common Name Bromoacetamido-PEG5-azide
CAS Number 1415800-37-1 Molecular Weight 427.29
Density N/A Boiling Point N/A
Molecular Formula C14H27BrN4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromoacetamido-PEG5-azide


Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromoacetamido-PEG5 -Azide

 Bromoacetamido-PEG5-azide Biological Activity

Description Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H27BrN4O6
Molecular Weight 427.29
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