86770-72-1

86770-72-1 structure

Name: Benzyl-PEG5-azide
Chemical Name: 16-Azido-1-phenyl-2,5,8,11,14-pentaoxahexadecane
CAS Number: 86770-72-1
Molecular Formula: C₁₇H₂₇N₃O₅
Molecular Weight: 353.413
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-21 14:40:52
Modify Date: 2024-01-09 12:09:47
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	16-Azido-1-phenyl-2,5,8,11,14-pentaoxahexadecane
Synonyms	16-Azido-1-phenyl-2,5,8,11,14-pentaoxahexadecane 2,5,8,11,14-Pentaoxahexadecane, 16-azido-1-phenyl- Benzyl-PEG5-azide

Description	Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562