Bromoacetamido-PEG2-C2-acid

Modify Date: 2025-09-12 08:27:54

Bromoacetamido-PEG2-C2-acid Structure
Bromoacetamido-PEG2-C2-acid structure
Common Name Bromoacetamido-PEG2-C2-acid
CAS Number 1415800-44-0 Molecular Weight 298.131
Density 1.5±0.1 g/cm3 Boiling Point 491.4±45.0 °C at 760 mmHg
Molecular Formula C9H16BrNO5 Melting Point N/A
MSDS N/A Flash Point 251.0±28.7 °C

 Use of Bromoacetamido-PEG2-C2-acid


Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-(2-{2-[(Bromoacetyl)amino]ethoxy}ethoxy)propanoic acid
Synonym More Synonyms

 Bromoacetamido-PEG2-C2-acid Biological Activity

Description Bromoacetamido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 491.4±45.0 °C at 760 mmHg
Molecular Formula C9H16BrNO5
Molecular Weight 298.131
Flash Point 251.0±28.7 °C
Exact Mass 297.021179
LogP -0.59
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.503

 Synonyms

MFCD22683317
Propanoic acid, 3-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]-
3-(2-{2-[(Bromoacetyl)amino]ethoxy}ethoxy)propanoic acid
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