IDH1 Inhibitor 3

Modify Date: 2024-01-12 10:17:03

IDH1 Inhibitor 3 structure	Common Name	IDH1 Inhibitor 3
	CAS Number	2171081-24-4	Molecular Weight	591.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₂₅F₄N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDH1 Inhibitor 3

IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1].

Name	IDH1 Inhibitor 3

Description	IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)
Target	IC50: 45 nM (IDH1R132H)[1].
References	[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.

Molecular Formula	C₃₁H₂₅F₄N₅O₃
Molecular Weight	591.56