TAK-070 Free base

Modify Date: 2024-01-28 11:02:00

TAK-070 Free base structure	Common Name	TAK-070 Free base
	CAS Number	212571-56-7	Molecular Weight	385.54
	Density	1.058±0.06 g/cm3(Predicted)	Boiling Point	534.8±50.0 °C(Predicted)
	Molecular Formula	C₂₇H₃₁NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TAK-070 Free base

TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].

Name	TAK-070

Description	TAK-070 Free base is a noncompetitive and orally active BACE1 inhibitor (IC50: 3.15 μM). TAK-070 Free base can be used for research of Alzheimer’s disease (AD). TAK-070 Free base inhibits brain levels of soluble Aβ, and improves cognitive impairments in AD model[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
Target	3.15 μM (BACE1)[1].
References	[1]. Fukumoto H, et al. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66.

Density	1.058±0.06 g/cm3(Predicted)
Boiling Point	534.8±50.0 °C(Predicted)
Molecular Formula	C₂₇H₃₁NO
Molecular Weight	385.54

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TAK-070 Free base

Use of TAK-070 Free base

Names

TAK-070 Free base Biological Activity

Chemical & Physical Properties