Aviculin
Modify Date: 2023-02-23 11:13:18
Aviculin structure
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Common Name | Aviculin | ||
|---|---|---|---|---|
| CAS Number | 156765-33-2 | Molecular Weight | 506.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H34O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AviculinAviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1]. |
| Name | Aviculin |
|---|
| Description | Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio[1]. |
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| Related Catalog | |
| Target |
Caspase-9 Caspase-7 Bcl-2 Bax PARP |
| References |
| Molecular Formula | C26H34O10 |
|---|---|
| Molecular Weight | 506.54 |