4-FLUORO-4'-BROMOCHALCONE
Modify Date: 2024-01-13 16:39:03
4-FLUORO-4'-BROMOCHALCONE structure
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Common Name | 4-FLUORO-4'-BROMOCHALCONE | ||
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| CAS Number | 98991-32-3 | Molecular Weight | 305.14 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H10BrFO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-FLUORO-4'-BROMOCHALCONECHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1]. |
| Name | 1-(4-bromophenyl)-3-(4-fluorophenyl)prop-2-en-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species (ROS). CHBO4 can be used for Parkinson's Disease (PD) research[1]. |
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| Related Catalog | |
| Target |
hMAO-B:0.031 μM (IC50) hMAO-B:0.010 μM (Ki) |
| References |
| Molecular Formula | C15H10BrFO |
|---|---|
| Molecular Weight | 305.14 |
| Exact Mass | 303.99000 |
| PSA | 17.07000 |
| LogP | 4.48430 |
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~98%
4-FLUORO-4'-BRO... CAS#:98991-32-3 |
| Literature: Tiwari, Urvashi; Ameta, Chetna; Rawal, Manish K.; Ameta, Rakshit; Punjabi, Pinki B. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 3 p. 432 - 439 |
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~18%
4-FLUORO-4'-BRO... CAS#:98991-32-3
Detail
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| Literature: El-Bayouki; Basyouni; El-Sayed; Tohamy; El-Henawy Croatica Chemica Acta, 2012 , vol. 85, # 3 p. 255 - 268 |
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~18%
4-FLUORO-4'-BRO... CAS#:98991-32-3
Detail
|
| Literature: El-Bayouki; Basyouni; El-Sayed; Tohamy; El-Henawy Croatica Chemica Acta, 2012 , vol. 85, # 3 p. 255 - 268 |
| Precursor 3 | |
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| DownStream 0 | |
| 2-Propen-1-one,1-(4-bromophenyl)-3-(4-fluorophenyl) |
| 4-Fluoro-4'-bromochalcone |