MAO-B inhibitor 8f

Modify Date: 2024-02-04 23:35:31

MAO-B inhibitor 8f Structure
MAO-B inhibitor 8f structure
Common Name MAO-B inhibitor 8f
CAS Number 947540-06-9 Molecular Weight 359.367
Density N/A Boiling Point N/A
Molecular Formula C15H16F3N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAO-B inhibitor 8f


A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.

 Names

Name MAO-B inhibitor 8f

 MAO-B inhibitor 8f Biological Activity

Description A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.
References References 1. Kaplan A, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2746-2758. View Related Products by Target Monoamine Oxidase (MAO)

 Chemical & Physical Properties

Molecular Formula C15H16F3N3O2S
Molecular Weight 359.367
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