947540-06-9
947540-06-9 structure
- Name: MAO-B inhibitor 8f
- Chemical Name: MAO-B inhibitor 8f
- CAS Number: 947540-06-9
- Molecular Formula: C15H16F3N3O2S
- Molecular Weight: 359.367
- Create Date: 2020-01-11 18:21:51
- Modify Date: 2025-08-25 10:44:06
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A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.
| Name | MAO-B inhibitor 8f |
|---|
| Description | A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs. |
|---|---|
| References | References 1. Kaplan A, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2746-2758. View Related Products by Target Monoamine Oxidase (MAO) |
| Molecular Formula | C15H16F3N3O2S |
|---|---|
| Molecular Weight | 359.367 |