VTP-27999
Modify Date: 2025-08-26 09:10:39
VTP-27999 structure
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Common Name | VTP-27999 | ||
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| CAS Number | 942142-51-0 | Molecular Weight | 525.08100 | |
| Density | 1.178g/cm3 | Boiling Point | 703.1ºC at 760 mmHg | |
| Molecular Formula | C26H41ClN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 379ºC | |
Use of VTP-27999VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.Ic50 value:Target: Renin |
| Name | methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate |
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| Synonym | More Synonyms |
| Description | VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.Ic50 value:Target: Renin |
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| Related Catalog | |
| References |
| Density | 1.178g/cm3 |
|---|---|
| Boiling Point | 703.1ºC at 760 mmHg |
| Molecular Formula | C26H41ClN4O5 |
| Molecular Weight | 525.08100 |
| Flash Point | 379ºC |
| Exact Mass | 524.27700 |
| PSA | 101.16000 |
| LogP | 4.69060 |
| Index of Refraction | 1.537 |
| InChIKey | NXWASIVXQMMPLM-ZXMXYHOLSA-N |
| SMILES | CNC(CNC(=O)N1CCCC(C(OCCNC(=O)OC)c2cccc(Cl)c2)C1)CC1CCCOC1 |
| Storage condition | 2-8℃ |
|
~91%
VTP-27999 CAS#:942142-51-0 |
| Literature: VITAE PHARMACEUTICALS, INC.; CLAREMON, David, A.; SIMPSON, Robert, D.; JIA, Lanqi Patent: WO2011/17533 A1, 2011 ; Location in patent: Page/Page column 24 ; |
| Precursor 1 | |
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| DownStream 0 | |
| Methyl (2-{(R)-(3-Chlorophenyl)[(3r)-1-({(2s)-2-(Methylamino)-3-[(3r)-Tetrahydro-2h-Pyran-3-Yl]propyl}carbamoyl)piperidin-3-Yl]methoxy}ethyl)carbamate |
| Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate |
| QC-4593 |
| VTP-27999 |