VTP-27999 (Hydrochloride)

Modify Date: 2024-01-24 20:24:14

VTP-27999 (Hydrochloride) structure	Common Name	VTP-27999 (Hydrochloride)
	CAS Number	1264191-73-2	Molecular Weight	561.54100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₂Cl₂N₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VTP-27999 (Hydrochloride)

VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:Target: Renin

Name	methyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate hydrochloride
Synonym	More Synonyms

Description	VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:Target: Renin
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Renin Research Areas >> Cardiovascular Disease
References	[1]. Lanqi Jia et al. Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility ACS Med. Chem. Lett., 2011, 2 (10), pp 747-751 [2]. New renin inhibitor VTP-27999 alters renin immunoreactivity and does not unfold prorenin. Hypertension. 2013 May;61(5):1075-1082. [3]. Ishchenko A, et al. Structure-based design technology contour and its application to the design of Renin inhibitors.J Chem Inf Model. 2012 Aug 27;52(8):2089-97. Epub 2012 Jul 25.

Description

VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.IC50 value:Target: Renin

Related Catalog

Signaling Pathways >> Metabolic Enzyme/Protease >> Renin

Research Areas >> Cardiovascular Disease

References