Lipoamide

Modify Date: 2025-08-21 18:33:19

Lipoamide Structure
Lipoamide structure
 Common Name Lipoamide
CAS Number 940-69-2 Molecular Weight 205.34100
Density 1.169 g/cm3 Boiling Point 399.2ºC at 760 mmHg
Molecular Formula C8H15NOS2 Melting Point 127-129ºC(lit.)
MSDS Chinese USA Flash Point 195.2ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Lipoamide


Lipoamide is a coenzyme, which transfer acetyl and hydrogen in Pyruvate deacylation oxidation Process, used for pharmaceuticals.

 Names

Name lipoamide
Synonym More Synonyms

 Lipoamide Biological Activity

Description Lipoamide is a coenzyme, which transfer acetyl and hydrogen in Pyruvate deacylation oxidation Process, used for pharmaceuticals.
Related Catalog

 Chemical & Physical Properties

Density 1.169 g/cm3
Boiling Point 399.2ºC at 760 mmHg
Melting Point 127-129ºC(lit.)
Molecular Formula C8H15NOS2
Molecular Weight 205.34100
Flash Point 195.2ºC
Exact Mass 205.06000
PSA 93.69000
LogP 2.88610
Index of Refraction 1.562
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JP1185000
CHEMICAL NAME :
1,2-Dithiolane-3-valeramide
CAS REGISTRY NUMBER :
940-69-2
BEILSTEIN REFERENCE NO. :
0122470
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C8-H15-N-O-S2
MOLECULAR WEIGHT :
205.36
WISWESSER LINE NOTATION :
T5SSTJ C4VZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1980 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,454,1982

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Hazard Codes Xn
Risk Phrases R22
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS JP1185000
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles42

More Articles
Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.

Cell 159(7) , 1615-25, (2014)

Sirtuins (SIRTs) are critical enzymes that govern genome regulation, metabolism, and aging. Despite conserved deacetylase domains, mitochondrial SIRT4 and SIRT5 have little to no deacetylase activity,...

Molecular characterization of the thioredoxin system from Methanosarcina acetivorans.

FEBS J. 281(20) , 4598-611, (2014)

The thioredoxin system, composed of thioredoxin reductase (TrxR) and thioredoxin (Trx), is widely distributed in nature, where it serves key roles in electron transfer and in the defense against oxida...

Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level.

Biochemistry 42(7) , 2218-28, (2003)

Lipoamide dehydrogenase catalyzes the reversible NAD(+)-dependent oxidation of the dihydrolipoyl cofactors that are covalently attached to the acyltransferase components of the pyruvate dehydrogenase,...

 Synonyms

lipoicin
dl-thioctic acid amide
thioami
5-(1,2-Dithiolan-3-yl)pentanamide
EINECS 213-375-2
vitaminn
MFCD00005475
thioctic amide
lipozyme
lypoaran
lipoacin
ticolin
lipoamid
lipamide
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Related Compounds: More...
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1334172-73-4
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1114828-04-4
Chemsrc provides Lipoamide(CAS#:940-69-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Lipoamide are included as well.>> amp version: Lipoamide

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