AS 1892802

Modify Date: 2023-10-18 20:28:04

AS 1892802 structure	Common Name	AS 1892802
	CAS Number	928320-12-1	Molecular Weight	333.38400
	Density	1.256±0.06 g/cm3 (20 °C, 760 mmHg)	Boiling Point	531.2±50.0 °C (760 mmHg)
	Molecular Formula	C₂₀H₁₉N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AS 1892802

AS1892802 is a potent, orally active, and highly selective inhibitor of ROCK. The onset of antinociceptive effect of AS1892802 is as fast as those of Tramadol and Diclofenac. AS1892802 did not induce gastric irritation or abnormal behavior. AS1892802 is an attractive analgesic profile for the research of severe osteoarthritis pain[1].

Name	Urea, N-[(1S)-2-hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]

Description	AS1892802 is a potent, orally active, and highly selective inhibitor of ROCK. The onset of antinociceptive effect of AS1892802 is as fast as those of Tramadol and Diclofenac. AS1892802 did not induce gastric irritation or abnormal behavior. AS1892802 is an attractive analgesic profile for the research of severe osteoarthritis pain[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Research Areas >> Neurological Disease Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK
References	[1]. Yoshimi E, et al. Antinociceptive effects of AS1892802, a novel Rho kinase inhibitor, in rat models of inflammatory and noninflammatory arthritis. J Pharmacol Exp Ther. 2010;334(3):955-963.

Density	1.256±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point	531.2±50.0 °C (760 mmHg)
Molecular Formula	C₂₀H₁₉N₃O₂
Molecular Weight	333.38400
Exact Mass	333.14800
PSA	74.25000
LogP	4.06760

DC Chemicals Limited
China
Product Name: AS1892802
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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