NH2-PEG3 hydrochloride

Modify Date: 2024-02-01 11:24:36

NH2-PEG3 hydrochloride Structure
NH2-PEG3 hydrochloride structure
Common Name NH2-PEG3 hydrochloride
CAS Number 92505-84-5 Molecular Weight 185.64900
Density N/A Boiling Point N/A
Molecular Formula C6H16ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG3 hydrochloride


NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-(2-aminoethoxy)ethoxy]ethanol,hydrochloride
Synonym More Synonyms

 NH2-PEG3 hydrochloride Biological Activity

Description NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C6H16ClNO3
Molecular Weight 185.64900
Exact Mass 185.08200
PSA 64.71000
LogP 0.47290

 Synonyms

MFCD28963473
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