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92505-84-5

92505-84-5 structure
92505-84-5 structure
  • Name: NH2-PEG3 hydrochloride
  • Chemical Name: 2-[2-(2-aminoethoxy)ethoxy]ethanol,hydrochloride
  • CAS Number: 92505-84-5
  • Molecular Formula: C6H16ClNO3
  • Molecular Weight: 185.64900
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-03-05 15:31:18
  • Modify Date: 2024-02-01 11:24:36
  • NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-(2-aminoethoxy)ethoxy]ethanol,hydrochloride
Synonyms MFCD28963473
Description NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H16ClNO3
Molecular Weight 185.64900
Exact Mass 185.08200
PSA 64.71000
LogP 0.47290