Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: NH2-PEG3-C2-Boc
Price: ￥2140.0/1g ￥8620.0/5g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Propanoic acid,3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
Price: ￥Inquiry/10g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

DC Chemicals Limited
China
Product Name: Amino-PEG3-t-butyl ester
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

252881-74-6

252881-74-6 structure

252881-74-6 structure

Name: NH2-PEG3-C2-Boc
Chemical Name: tert-butyl 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoate
CAS Number: 252881-74-6
Molecular Formula: C₁₃H₂₇NO₅
Molecular Weight: 277.35700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-10-15 10:35:21
Modify Date: 2024-01-04 20:29:14
NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-butyl 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoate
Synonyms	H2N-OEG-CO2tBu tert-butyl 3-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}propanoate tert-Butyl 3-[2-(2-(2-aminoethoxy)ethoxy)ethoxy]propionate NH2(CH2CH2O)3CH2CH2COOt-Bu 12-amino-4,7,10-trioxadodecanoic acid tert-butyl ester Amin PEG3-t-butyl ester tert-butyl 12-amino-4,7,10-trioxododecanoate tert-Butyl 12-amino-4,7,10-trioxadodecanoate 3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester

Description	NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₃H₂₇NO₅
Molecular Weight	277.35700
Flash Point	169.7ºC
Exact Mass	277.18900
PSA	80.01000
LogP	1.42700

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26
HS Code	2922509090

252881-73-5 structure

252881-73-5

~%

252881-74-6 structure

252881-74-6

Literature: US2006/205670 A1, ; Page/Page column 105 ;

Precursor 1
252881-73-5
DownStream 1
518044-40-1

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%