SARS-CoV-2 nsp13-IN-4
Modify Date: 2025-08-25 10:31:27
SARS-CoV-2 nsp13-IN-4 structure
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Common Name | SARS-CoV-2 nsp13-IN-4 | ||
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| CAS Number | 923140-39-0 | Molecular Weight | 407.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15BrN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SARS-CoV-2 nsp13-IN-4SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1]. |
| Name | SARS-CoV-2 nsp13-IN-4 |
|---|
| Description | SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1]. |
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| Related Catalog | |
| Target |
IC50: 57 μM (nsp13 ssDNA+ ATPase) [1] |
| In Vitro | SARS-CoV-2 nsp13-IN-4 (C4 (d)) inhibits the ssDNA+ ATPase activity and the ssDNA− ATPase activity of nsp13 with IC50 values of 57 μM and 240 μM, respectively[1]. |
| References |
| Molecular Formula | C20H15BrN4O |
|---|---|
| Molecular Weight | 407.26 |
| InChIKey | JJNZRWKEVHQYEP-UHFFFAOYSA-N |
| SMILES | Cc1ccn2cc(-c3ccc(NC(=O)c4cccc(Br)c4)cc3)nc2n1 |