1005304-44-8

1005304-44-8 structure

Name: SARS-CoV-2 nsp13-IN-1
Chemical Name: SARS-CoV-2 nsp13-IN-1
CAS Number: 1005304-44-8
Molecular Formula: C₂₇H₂₀N₄O₂
Molecular Weight: 432.47
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-09-01 15:31:19
Modify Date: 2025-09-30 18:02:02
SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].

Name	SARS-CoV-2 nsp13-IN-1

Description	SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 6 ± 0.5 μM (nsp13 ssDNA+ ATPase)[1]
References	[1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Molecular Formula	C₂₇H₂₀N₄O₂
Molecular Weight	432.47