SARS-CoV-2 nsp13-IN-1

Modify Date: 2025-09-30 18:02:02

SARS-CoV-2 nsp13-IN-1 Structure
SARS-CoV-2 nsp13-IN-1 structure
 Common Name SARS-CoV-2 nsp13-IN-1
CAS Number 1005304-44-8 Molecular Weight 432.47
Density N/A Boiling Point N/A
Molecular Formula C27H20N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2 nsp13-IN-1


SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].

 Names

Name SARS-CoV-2 nsp13-IN-1

 SARS-CoV-2 nsp13-IN-1 Biological Activity

Description SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research[1].
Related Catalog
Target

IC50: 6 ± 0.5 μM (nsp13 ssDNA+ ATPase)[1]

References

[1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

 Chemical & Physical Properties

Molecular Formula C27H20N4O2
Molecular Weight 432.47
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