923140-39-0

923140-39-0 structure

Name: SARS-CoV-2 nsp13-IN-4
Chemical Name: SARS-CoV-2 nsp13-IN-4
CAS Number: 923140-39-0
Molecular Formula: C₂₀H₁₅BrN₄O
Molecular Weight: 407.26
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-09-01 12:28:08
Modify Date: 2025-08-25 10:31:27
SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].

Name	SARS-CoV-2 nsp13-IN-4

Description	SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is druglike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 57 μM (nsp13 ssDNA+ ATPase) [1]
In Vitro	SARS-CoV-2 nsp13-IN-4 (C4 (d)) inhibits the ssDNA+ ATPase activity and the ssDNA− ATPase activity of nsp13 with IC50 values of 57 μM and 240 μM, respectively[1].
References	[1]. Aliakbar Khalili Yazdi, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Molecular Formula	C₂₀H₁₅BrN₄O
Molecular Weight	407.26