tert-Butyl prop-2-yn-1-ylcarbamate

Modify Date: 2024-01-14 17:27:51

tert-Butyl prop-2-yn-1-ylcarbamate Structure
tert-Butyl prop-2-yn-1-ylcarbamate structure
Common Name tert-Butyl prop-2-yn-1-ylcarbamate
CAS Number 92136-39-5 Molecular Weight 155.19
Density 1.0±0.1 g/cm3 Boiling Point 222.5±23.0 °C at 760 mmHg
Molecular Formula C8H13NO2 Melting Point 40-44ºC
MSDS Chinese USA Flash Point 88.4±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of tert-Butyl prop-2-yn-1-ylcarbamate


N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name N-Boc-Propargylamine
Synonym More Synonyms

 tert-Butyl prop-2-yn-1-ylcarbamate Biological Activity

Description N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro N-Boc-propargylamine 用于制备三唑并亚苄基-噻唑并嘧啶。作为 CDC25 磷酸酶抑制剂。此外,它还用于合成 β-葡聚糖多糖类似物。除此之外,它还参与降冰片二烯和 N-Boc-炔丙胺的 Pauson-Kh 和 (PK) 反应,制备 4,5-二取代环戊烯酮。

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 222.5±23.0 °C at 760 mmHg
Melting Point 40-44ºC
Molecular Formula C8H13NO2
Molecular Weight 155.19
Flash Point 88.4±22.6 °C
Exact Mass 155.094635
PSA 41.82000
LogP 1.50
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.452

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22;R36/37/38;R52/53
Safety Phrases 26-36/37-61
RIDADR NONH for all modes of transport
HS Code 2924199090

 Synthetic Route

~99%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: Ishida, Tomonobu; Kobayashi, Ryo; Yamada, Tohru Organic Letters, 2014 , vol. 16, # 9 p. 2430 - 2433

~97%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: PFIZER PRODUCTS INC. Patent: WO2004/56830 A1, 2004 ; Location in patent: Page 86 ;

~78%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: Dickson, Hamilton D.; Smith, Stephon C.; Hinkle, Kevin W. Tetrahedron Letters, 2004 , vol. 45, # 29 p. 5597 - 5599

~%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: Advanced Synthesis and Catalysis, , vol. 351, # 9 p. 1371 - 1377

~%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: Journal of Organic Chemistry, , vol. 79, # 3 p. 1254 - 1264

~%

tert-Butyl prop-2-yn-1-ylcarbamate Structure

tert-Butyl prop...

CAS#:92136-39-5

Literature: Tetrahedron, , vol. 52, # 20 p. 7037 - 7044

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Carbamic acid, N-2-propyn-1-yl-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 2-propyn-1-ylcarbamate
tert-Butyl prop-2-yn-1-ylcarbamate
tert-butyl N-prop-2-ynylcarbamate