Benzyl-PEG2-CH2COOH

Modify Date: 2024-01-07 10:40:47

Benzyl-PEG2-CH2COOH Structure
Benzyl-PEG2-CH2COOH structure
Common Name Benzyl-PEG2-CH2COOH
CAS Number 91842-53-4 Molecular Weight 254.279
Density 1.2±0.1 g/cm3 Boiling Point 409.7±30.0 °C at 760 mmHg
Molecular Formula C13H18O5 Melting Point N/A
MSDS N/A Flash Point 152.5±18.1 °C

 Use of Benzyl-PEG2-CH2COOH


Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
Synonym More Synonyms

 Benzyl-PEG2-CH2COOH Biological Activity

Description Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 409.7±30.0 °C at 760 mmHg
Molecular Formula C13H18O5
Molecular Weight 254.279
Flash Point 152.5±18.1 °C
Exact Mass 254.115417
PSA 64.99000
LogP 0.68
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.514

 Synonyms

Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-
10-phenyl-3,6,9-trioxadecanoic acid
{2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
2-(2-(2-(Benzyloxy)ethoxy)ethoxy)acetic acid
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