91842-53-4
91842-53-4 structure
- Name: Benzyl-PEG2-CH2COOH
- Chemical Name: {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid
- CAS Number: 91842-53-4
- Molecular Formula: C13H18O5
- Molecular Weight: 254.279
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-05-20 06:32:35
- Modify Date: 2025-09-06 16:13:40
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Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid |
|---|---|
| Synonyms |
Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-
10-phenyl-3,6,9-trioxadecanoic acid {2-[2-(Benzyloxy)ethoxy]ethoxy}acetic acid 2-(2-(2-(Benzyloxy)ethoxy)ethoxy)acetic acid |
| Description | Benzyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 409.7±30.0 °C at 760 mmHg |
| Molecular Formula | C13H18O5 |
| Molecular Weight | 254.279 |
| Flash Point | 152.5±18.1 °C |
| Exact Mass | 254.115417 |
| PSA | 64.99000 |
| LogP | 0.68 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.514 |
|
~51%
91842-53-4 |
| Literature: Czech, Bronislaw P.; Bartsch, Richard A. Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4076 - 4078 |
