2050-25-1
2050-25-1 structure
- Name: Diethylene Glycol Monobenzyl Ether
- Chemical Name: 2-(2-phenylmethoxyethoxy)ethanol
- CAS Number: 2050-25-1
- Molecular Formula: C11H16O3
- Molecular Weight: 196.243
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-05-11 08:00:00
- Modify Date: 2024-01-02 05:47:51
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Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-(2-phenylmethoxyethoxy)ethanol |
|---|---|
| Synonyms |
Ethanol, 2-[2-(phenylmethoxy)ethoxy]-
2-[2-(Benzyloxy)ethoxy]ethanol Ethanol, 2-[2-(benzyloxy)ethoxy]- Ethanol, 2-[2- (phenylmethoxy)ethoxy]- Diethylene Glycol Monobenzyl Ether MFCD00029649 Ethanol, 2-[2- (benzyloxy)ethoxy]- |
| Description | Diethylene Glycol Monobenzyl Ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 311.2±22.0 °C at 760 mmHg |
| Molecular Formula | C11H16O3 |
| Molecular Weight | 196.243 |
| Flash Point | 142.0±22.3 °C |
| Exact Mass | 196.109940 |
| PSA | 38.69000 |
| LogP | 0.90 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.513 |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2909499000 |
| Precursor 9 | |
|---|---|
| DownStream 5 | |
| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |