Benzyl-PEG2-azide

Modify Date: 2024-01-12 18:23:49

Benzyl-PEG2-azide Structure
Benzyl-PEG2-azide structure
Common Name Benzyl-PEG2-azide
CAS Number 1260001-87-3 Molecular Weight 221.256
Density N/A Boiling Point N/A
Molecular Formula C11H15N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG2-azide


Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name {[2-(2-Azidoethoxy)ethoxy]methyl}benzene
Synonym More Synonyms

 Benzyl-PEG2-azide Biological Activity

Description Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Steinebach C, et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm. 2019 May 28;10(6):1037-1041.

 Chemical & Physical Properties

Molecular Formula C11H15N3O2
Molecular Weight 221.256
Exact Mass 221.116425
LogP 1.90

 Synonyms

{[2-(2-Azidoethoxy)ethoxy]methyl}benzene
MFCD28064332
Benzene, [[2-(2-azidoethoxy)ethoxy]methyl]-
Benzyl-PEG2-azide
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