CCMI
Modify Date: 2025-08-25 16:46:52
CCMI structure
|
Common Name | CCMI | ||
|---|---|---|---|---|
| CAS Number | 917837-54-8 | Molecular Weight | 388.24700 | |
| Density | 1.412±0.06 g/cm3(Predicted) | Boiling Point | 605.4±55.0 °C | |
| Molecular Formula | C19H15Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CCMICCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1]. |
| Name | (Z)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide |
|---|---|
| Synonym | More Synonyms |
| Description | CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1]. |
|---|---|
| Related Catalog | |
| Target |
α7 nAChR[1] |
| In Vitro | CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs[1]. |
| References |
| Density | 1.412±0.06 g/cm3(Predicted) |
|---|---|
| Boiling Point | 605.4±55.0 °C |
| Molecular Formula | C19H15Cl2N3O2 |
| Molecular Weight | 388.24700 |
| Exact Mass | 387.05400 |
| PSA | 67.16000 |
| LogP | 5.52750 |
| Hazard Codes | Xn |
|---|
| MFCD18086897 |