AMG-1
Modify Date: 2025-08-28 15:07:20
AMG-1 structure
|
Common Name | AMG-1 | ||
|---|---|---|---|---|
| CAS Number | 913376-84-8 | Molecular Weight | 556.584 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C31H29FN4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AMG-1AMG-1 is a potent inhibitor of human c-Met and RON with IC50 values of 4 and 9 nmol/L respectively. |
| Name | 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl |
|---|---|
| Synonym | More Synonyms |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C31H29FN4O5 |
| Molecular Weight | 556.584 |
| Exact Mass | 556.212219 |
| PSA | 107.61000 |
| LogP | 4.39 |
| Index of Refraction | 1.660 |
| InChIKey | UYMSIPINLJNNOU-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 |
| Hazard Codes | Xn |
|---|
| N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide |
| MET/RON DUAL KINASE INHIBITOR |
| 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl- |
| N-{3-Fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide |
| AMG-1 |